Existing research is often hampered by small sample sizes, inadequate control groups (making comparisons difficult), and lack of publication in reputable journals
Medicare Part D is an optional benefit that covers a wide range of prescription drugs
The headline results at 80 weeks were: 12 mg dose: average weight loss of 28.3% (approximately 70.3 lbs / 31.9 kg) 9 mg dose: average weight loss of 25.9% (approximately 64.4 lbs / 29.2 kg) 4 mg dose: average weight loss of 19.0% (approximately 47.2 lbs / 21.4 kg) Placebo: average weight loss of just 2.2% Perhaps most striking was the proportion of patients hitting bariatric-surgery-level outcomes: at the highest dose, 45.3% of participants lost 30% or more of their body weight , and 65.3% reduced their BMI to below 30 kg/m meaning they were no longer classified as living with obesity by the end of the trial
Treat these as warning signs that a source is not legitimate: no prescription required, a pharmacy located outside the United States, packaging that is damaged, opened, unlabeled in English, or missing an expiration date, and ingredient lists described only as proprietary blends
That said, GLP-1s are not bad for most people